ARIXTRA provides efficacy with ease with simple once-daily dosing

Dosing for the treatment of DVT and PE

Dosing for prohylaxis of DVT and PE


ARIXTRA dosing for the TREATMENT of DVT and PE

In the MATISSE DVT trial, 85% of patients in the group treated with ARIXTRA received the 7.5-mg dose

  • Concomitant treatment with warfarin should be initiated as soon as possible, usually within 72 hours.
  • A therapeutic oral anticoagulant effect (INR of 2.0 to 3.0) should be established prior to discontinuation of ARIXTRA.
  • The usual duration of administration with ARIXTRA is 5-9 days.

ARIXTRA dosing for the PROPHYLAXIS* of DVT and PE

ARIXTRA dosing for the PROPHYLAXIS of DVT and PE

*In patients undergoing hip replacement, knee replacement, hip fracture surgery, or abdominal surgery at risk of thromboembolic complications.
†Contraindicated for prophylaxis in patients <50 kg.
  • The usual length of therapy for ARIXTRA is between 5 and 9 days.
  • In patients undergoing extended prophylaxis following hip fracture surgery, ARIXTRA has been administered for as many as 32 days.
  • The initial dose of ARIXTRA is recommended to be given 6 to 8 hours following surgery, after hemostasis has been established; administration before 6 hours after surgery has been associated with an increased risk of major bleeding.

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Please see Important Safety Information and complete Prescribing Information, including BOXED WARNING
regarding epidural and spinal hematomas.